Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.

doi:10.1371/journal.pone.0026987

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Article

Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis: case-control studies.

PloS one - 1 Jan 2011

Hirota Tomomitsu, Saeki Hidehisa, Tomita Kaori, Tanaka Shota, Ebe Kouji, Sakashita Masafumi, Yamada Takechiyo, Fujieda Shigeharu, Miyatake Akihiko, Doi Satoru, Enomoto Tadao, Hizawa Nobuyuki, Sakamoto Tohru, Masuko Hironori, Sasaki Takashi, Ebihara Tamotsu, Amagai Masayuki, Esaki Hitokazu, Takeuchi Satoshi, Furue Masutaka, Noguchi Emiko, Kamatani Naoyuki, Nakamura Yusuke, Kubo Michiaki, Tamari Mayumi

Abstract excerpt

Atopic dermatitis (AD) is a common inflammatory skin disease caused by multiple genetic and environmental factors. AD is characterized by the local infiltration of T helper type 2 (Th2) cells. Recent clinical studies have shown important roles of the Th2 chemokines, CCL22 and CCL17 in the pathogenesis of AD. To investigate whether polymorphisms of the CCL22 gene affect the susceptibility to AD, we conducted...

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Identifiers

PMID: 22125604
DOI: 10.1371/journal.pone.0026987
PMCID: PMC3219642

Genes

CCL22
CCL17

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Source receipt: pubmed, retrieved 7 Sept 2026.

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