Article
Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter.
Experimental neurology - 1 Feb 1999
Bezard E, Gross C E, Fournier M C, Dovero S, Bloch B, Jaber M
Abstract excerpt
MPTP has been shown to induce parkinsonism both in human and in nonhuman primates. The precise mechanism of dopaminergic cell death induced following MPTP treatment is still subject to intense debate. MPP+, which is the oxidation product of MPTP, is actively transported into presynaptic dopaminer...
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