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Article

Age-related changes in nigrostriatal dopaminergic function in heterozygous mutant dopamine transporter knock-out mice.

Neuroscience letters - 31 May 2010

Dluzen Dean E, Ji Jing, McDermott Janet L

Abstract excerpt

In this report we compared three different parameters of nigrostriatal dopaminergic (NSDA) function - locomotor activity, striatal dopamine (DA) levels and 3,4-dihydroxyphenylacetic acid (DOPAC)/DA ratios between heterozygous mutant dopamine transporter mice (+/- DAT) and their wild type controls (+/+ DAT) at three different age range periods: 4-10, 11-17 and 18-24 months of age. Locomotor activity of the +/- DAT...

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Identifiers

PMID: 20382201
DOI: 10.1016/j.neulet.2010.04.004

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