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Article

The mouse MPTP model: gene expression changes in dopaminergic neurons

1 Jan 2003

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by the progressive loss of dopaminergic neurons in the substantia nigra. Although valuable animal models have been developed, our knowledge of the aetiology and pathogenic factors implicated in PD is still insufficient to develop causal therapeutic strategies aimed at halting its progression. The neurotoxicity induced by...

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PMID: 12534964
DOI: 10.1046/j.1460-9568.2003.02408.x

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