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Article

L-Dopa treatment abolishes the numerical increase in striatal dopaminergic neurons in parkinsonian monkeys.

Journal of chemical neuroanatomy - 1 Jan 2008

Huot Philippe, Lévesque Martin, Morissette Marc, Calon Frédéric, Dridi Mehdi, Di Paolo Thérèse, Parent André

Abstract excerpt

The striatum harbors a population of dopaminergic interneurons that increases in number in animal models of Parkinson's disease (PD), presumably to compensate for dopamine (DA) depletion. The purpose of the present study was to determine the fate of striatal dopaminergic neurons in parkinsonian monkeys in which striatal DA depletion had been alleviated by systemic administration of l-dopa. The number of striatal...

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Identifiers

PMID: 17706922
DOI: 10.1016/j.jchemneu.2007.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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