Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of transforming growth factor-beta in cancer progression.

Future oncology (London, England) - 1 Dec 2006

Galliher Amy J, Neil Jason R, Schiemann William P

Abstract excerpt

Invasion and metastasis are the most lethal characteristics of cancer and the leading causes of cancer-related death. Transforming growth factor (TGF)-beta is a multifunctional cytokine that normally functions to prevent the uncontrolled proliferation of epithelial, endothelial and hematopoietic cells. Quite dichotomously, however, aberrant genetic or epigenetic events often negate the cytostatic function of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Transforming Growth Factor beta
Share to Antineoplastic Agents
Share to Disease Progression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Share to Neovascularization, Pathologic

Share to Signal Transduction

Share to TGF-β signaling in diseases

Source

Identifiers

PMID: 17155901
DOI: 10.2217/14796694.2.6.743

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of transforming growth factor-beta in cancer progression.PMID 17155901Read ↗

Transforming growth factor-β and the hallmarks of cancer.Semantic proximity Read ↗

Actions of TGF-beta as tumor suppressor and pro-metastatic factor in human cancer.Semantic proximity Read ↗

TGF-β Family Signaling in Tumor Suppression and Cancer Progression.Semantic proximity Read ↗

Role of Transforming Growth Factor Beta in Human CancerSemantic proximity Read ↗

TGF-β signaling in cancerSemantic proximity Read ↗

The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisSemantic proximity Read ↗

Dichotomous roles of TGF-β in human cancerSemantic proximity Read ↗

TGF<i>β</i>Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisSemantic proximity Read ↗

Escaping from the TGFbeta anti-proliferative control.Semantic proximity Read ↗

TGF- : Duality of Function Between Tumor Prevention and CarcinogenesisSemantic proximity Read ↗

TGF-β Signaling in Cancer: Mechanisms of Progression and Therapeutic TargetsSemantic proximity Read ↗

The TGF-beta family: signaling pathways, developmental roles, and tumor suppressor activities.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.