Article
BMP7 acts in murine lens placode development.
Developmental biology - 1 Mar 1999
Wawersik S, Purcell P, Rauchman M, Dudley A T, Robertson E J, Maas R
Abstract excerpt
Targeted inactivation of the Bmp7 gene in mouse leads to eye defects with late onset and variable penetrance (A. T. Dudley et al., 1995, Genes Dev. 9, 2795-2807; G. Luo et al., 1995, Genes Dev. 9, 2808-2820). Here we report that the expressivity of the Bmp7 mutant phenotype markedly increases in a C3H/He genetic background and that the phenotype implicates Bmp7 in the early stages of lens development....
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