Article
BMP 7 is required for nephrogenesis, eye development, and skeletal patterning.
Annals of the New York Academy of Sciences - 8 Jun 1996
Karsenty G, Luo G, Hofmann C, Bradley A
Abstract excerpt
In summary, the generation of BMP-7-deficient mice has provided additional evidence that this family of growth factors regulate many morphogenetic processes including but not limited to skeletal development. In particular our experiments demonstrate that BMP 7 acts as an early inducer of glomeruli formation, and that it is required for skeletal patterning and lens formation. Our results not only demonstrate that...
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