BMP 7 is required for nephrogenesis, eye development, and skeletal patterning.

doi:10.1111/j.1749-6632.1996.tb56247.x

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Article

BMP 7 is required for nephrogenesis, eye development, and skeletal patterning.

Annals of the New York Academy of Sciences - 8 Jun 1996

Karsenty G, Luo G, Hofmann C, Bradley A

Abstract excerpt

In summary, the generation of BMP-7-deficient mice has provided additional evidence that this family of growth factors regulate many morphogenetic processes including but not limited to skeletal development. In particular our experiments demonstrate that BMP 7 acts as an early inducer of glomerul...

Topics

Animals
Anophthalmos
Bone Morphogenetic Protein 7
Bone Morphogenetic Proteins
Bone and Bones
Eye Abnormalities
Humans
Kidney
Mice
Mice, Knockout
Morphogenesis
Mutation
Polydactyly
Proteins
Toes
Transforming Growth Factor beta

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