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Article

Accumulation of recombinant chromosomes and low fidelity of transmission of chromosome X DNA markers in gamma-ray-induced lymphomas lacking p53.

Molecular carcinogenesis - 1 Jan 1999

Koide N, Matsumoto Y, Kosugi S, Chou D, Sakai K, Hatakeyama K, Niwa O, Kominami R

Abstract excerpt

F1 offspring of male MSM male mice with a p53-deficient (knockout) allele and normal female BALB/c mice were backcrossed with MSM mice to produce N2 mice. Female F1 and N2 mice were irradiated with gamma-radiation, and thymic lymphomas were obtained from 69 F1 and 82 N2 mice heterozygous for X chromosome markers. Of these 151 mice, 91 carried a p53-deficient allele. These lymphomas were analyzed for allelic loss...

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Source

Identifiers

PMID: 10029411
DOI: 10.1002/(sici)1098-2744(199901)24:1<57::aid-mc8>3.0.co;2-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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