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Article

Assessment of apolipoprotein E genotype for β-amyloid status prediction.

Current Alzheimer research - 1 Jan 2021

Peña-Bautista Carmen, Álvarez-Sánchez Lourdes, García Lorena, Baquero Miguel, Cháfer-Pericás Consuelo

Abstract excerpt

BACKGROUND: Apolipoprotein E (ApoE) is the major genetic risk factor for sporadic Alzheimer's Disease (AD). Some studies showed a relationship between ApoE4 genotype and the cerebrospinal fluid (CSF) biomarkers (β-amyloid42, p-Tau, t-Tau), as well as with cognitive status. In this sense, it could be interesting to develop an approach to establish amyloid status in a minimally invasive way. METHODS: The present...

Topics

Alzheimer Disease
Amyloid beta-Peptides
Apolipoprotein E4
Apolipoproteins E
Biomarkers
Cognitive Dysfunction
Genotype
Humans
Peptide Fragments
tau Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34951383
DOI: 10.2174/1567205019666211223141524

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34951383-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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