Article
Role of Bovine Bone Morphogenetic Proteins in Bone Matrix Protein and Osteoblast-Related Gene Expression During Rat Bone Marrow Stromal Cell Differentiation
1 Nov 2005
Abstract excerpt
Bone morphogenetic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway evaluating the ability of certain BMPs to promote bone graft and fracture healing. To observe the mechanism of osteoinductive and bone formation, 100 microg of bovine BMP was tested during osteogenic differentiation of rat bone marrow stromal cells (MSCs) and C2C12 line culture for 14 and 28 days. We...
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