Article
Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro.
Journal of cellular physiology - 1 Oct 1997
Puleo D A
Abstract excerpt
Bone morphogenetic proteins (BMPs) induce osteoblastic responses in cultures of pluripotent mesenchymal cells. The effects of chronic treatment of these cells with BMPs and of withdrawal following exposure, however, have not been fully elucidated. Thus, the aim of this study was to obtain information about the duration of exposure to recombinant human BMP-2 (rhBMP-2) required for expression and retention of...
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