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Article

Rbf Regulates Drosophila Spermatogenesis via Control of Somatic Stem and Progenitor Cell Fate in the Larval Testis.

Stem cell reports - 13 Dec 2016

Dominado Nicole, La Marca John E, Siddall Nicole A, Heaney James, Tran Mai, Cai Yu, Yu Fengwei, Wang Hongyan, Somers W Gregory, Quinn Leonie M, Hime Gary R

Abstract excerpt

The Drosophila testis has been fundamental to understanding how stem cells interact with their endogenous microenvironment, or niche, to control organ growth in vivo. Here, we report the identification of two independent alleles for the highly conserved tumor suppressor gene, Retinoblastoma-family protein (Rbf), in a screen for testis phenotypes in X chromosome third-instar lethal alleles. Rbf mutant alleles...

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Identifiers

PMID: 27974223
DOI: 10.1016/j.stemcr.2016.11.007
PMCID: PMC5161748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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