Article

Regulation of midzone microtubule dynamics and abscission in human cells by CAMSAP2 and Kif2a

2026-05-06

Abstract excerpt

<h4>ABSTRACT</h4> The spindle midzone, an array of overlapping, antiparallel microtubules, contributes to chromosome segregation and cytokinesis. As cells exit mitosis, midzone microtubules reorganize to form the midbody, the location of cell abscission. The mechanisms governing microtubule dynamics during this transition remain incompletely understood. The microtubule depolymerase, Kif2a, has been shown to contr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ff597d65-7bc1-524f-a418-31eea901bb78
DOI: 10.64898/2026.05.01.722315

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Regulation of midzone microtubule dynamics and abscission in human cells by CAMSAP2 and Kif2aDOI 10.64898/2026.05.01.722315Read

The kinesin-4 family member KIF27 regulates mitotic progression, cytokinesis and genome stabilitySemantic proximity Read

High-resolution imaging reveals how the spindle midzone impacts chromosome movementSemantic proximity Read

Clks 1, 2 and 4 prevent chromatin breakage by regulating the Aurora B-dependent abscission checkpoint.Semantic proximity Read

Misaligned chromosomes that satisfy the spindle assembly checkpoint are a strong predictor of micronuclei formation in dividing cancer cellsSemantic proximity Read

PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone.Semantic proximity Read

Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast.Semantic proximity Read

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell divisionSemantic proximity Read

Functional Interaction of SKA and NDC80 Complexes at Kinetochores Promoting Anaphase Onset in MitosisSemantic proximity Read

An ATM-Chk2-INCENP pathway activates the abscission checkpoint.Semantic proximity Read

Gradual Compaction of the Central Spindle Decreases its Dynamicity as Revealed in PRC1 and EB1 Gene-Edited Human CellsSemantic proximity Read

Discrete regions of the kinesin-8 Kip3 tail differentially mediate astral microtubule stability and spindle disassembly.Semantic proximity Read

ARF6 GTPase protects the post-mitotic midbody from 14-3-3-mediated disintegration.Semantic proximity Read