Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of blood pressure and antihypertensive drug classes on intracranial aneurysm: a Mendelian randomization study.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Nov 2023

Zeng Youjie, Guo Ren, Cao Si, Yang Heng

Abstract excerpt

BACKGROUND: Blood pressure is a risk factor for intracranial aneurysms (IA). Nevertheless, whether various antihypertensive drug classes discriminate in reducing IA risk is unclear. METHODS: Genome-wide association study summary statistics for systolic blood pressure (SBP), diastolic blood pressure (DBP), IA (non-ruptured), and IA [subarachnoid hemorrhage (SAH)] were downloaded. To proxy the effects of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antihypertensive Agents
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Intracranial Aneurysm

Share to Mendelian Randomization Analysis

Share to Pharmacogenomic Variants

Share to Risk Assessment

Share to Subarachnoid Hemorrhage

Source

Identifiers

PMID: 37716106
DOI: 10.1016/j.jstrokecerebrovasdis.2023.107355

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of blood pressure and antihypertensive drug classes on intracranial aneurysm: a Mendelian randomization study.PMID 37716106Read ↗

Effects of blood lipids and lipid‐modifying drugs on intracranial aneurysmsSemantic proximity Read ↗

Phenome-wide Mendelian Randomization Analysis of Genetic Variants Linking Intracranial Aneurysm, Unruptured Aneurysm, and Subarachnoid HemorrhageSemantic proximity Read ↗

Drug classes affecting intracranial aneurysm risk: genetic correlation and Mendelian randomizationSemantic proximity Read ↗

A two-sample Mendelian randomization analysis of modifiable risk factors and intracranial aneurysms.Semantic proximity Read ↗

Promising Therapeutic Targets for Intracranial Aneurysms: A Systematic Druggable Genome-Wide Mendelian Randomization.Semantic proximity Read ↗

PRCP is a promising drug target for intracranial aneurysm rupture supported via multi-omics analysis.Semantic proximity Read ↗

Causal relationship between intracranial aneurysms and COVID-19: A bidirectional two-sample Mendelian randomization studySemantic proximity Read ↗

Atherosclerosis, Intracranial Aneurysms, and Intermediate Biomarkers: Real-World Observational and Mendelian Randomization ResearchSemantic proximity Read ↗

The causal association between lipid-lowering strategies and risk of intracranial aneurysms: A drug-target Mendelian randomization study.Semantic proximity Read ↗

Omega-3 fatty acids and intracranial aneurysms: a Mendelian randomization studySemantic proximity Read ↗

Effect of the Blood Pressure and Antihypertensive Drugs on Cerebral Small Vessel Disease: A Mendelian Randomization Study.Semantic proximity Read ↗

Sex differences in risk factor relationships with subarachnoid haemorrhage and intracranial aneurysms: A Mendelian Randomisation study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.