Article

Early body weight gain in TALLYHO/JngJ mice predicts adult diabetic phenotype, mimicking childhood obesity

2024-02-01

Abstract excerpt

Childhood obesity and type 2 diabetes are two emerging health issues worldwide. To analyze their underlying causes and develop prevention strategies, mouse models are urgently needed. We present novel insights into the polygenic TALLYHO/JngJ mouse model for diabetes. By precisely analyzing our original phenotypic data, we discovered that body weight at weaning age is the main predictor of the adult phenotype in TA...

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Literature Corpus work: b7dfe0b3-23b6-5481-a9f7-1944dcbbb522
DOI: 10.1101/2024.01.29.577705

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