Article

Integrins protect nociceptive neurons in models of paclitaxel-mediated peripheral sensory neuropathy

2019-11-04

Abstract excerpt

<h4>Summary</h4> Chemotherapy induced peripheral neuropathy (CIPN) is a major side effect from cancer treatment with no known method for prevention or cure in clinics. CIPN primarily affects unmyelinated nociceptive sensory terminals. Despite the high prevalence of CIPN, molecular and cellular mechanisms that lead to CIPN are still poorly understood. Here, we used a genetically tractable Drosophila model and pri...

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Literature Corpus work: feefe6c6-d1c0-51d8-a02a-70248fda2583
DOI: 10.1101/829655

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