Article

The transition from primary colorectal cancer to isolated peritoneal malignancy is associated with a hypermutant, hypermethylated state

2020-02-25

Abstract excerpt

<h4>ABSTRACT</h4> Coloretcal Peritoneal metastases (CPM) develop in 15% of colorectal cancers. Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS & HIPEC) is the current standard of care in selected patients with limited resectable CPM. Despite selection using known prognostic factors survival is varied and morbidity and mortality are relatively high. There is a need to improve patient selection an...

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Literature Corpus work: feead221-4ad6-5d98-919e-10b43d2e5681
DOI: 10.1101/2020.02.24.20027318

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