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Article

Comprehensive tumor profiling reveals unique molecular differences between peritoneal metastases and primary colorectal adenocarcinoma.

Journal of surgical oncology - 1 Jun 2020

Stein Matthew K, Williard Forrest W, Xiu Joanne, Tsao Miriam W, Martin Michael G, Deschner Benjamin W, Dickson Paxton V, Glazer Evan S, Yakoub Danny, Shibata David, Grothey Axel F, Philip Philip A, Hwang Jimmy J, Shields Anthony F, Marshall John L, Korn W Michael, Lenz Heinz-Josef, Deneve Jeremiah L

Abstract excerpt

BACKGROUND AND OBJECTIVES: Peritoneal metastases (PM) from primary colorectal cancer (pCRC) are associated with poor outcomes; however, molecular differences are not well defined. METHODS: We compared unpaired tumor profiles of patients with pCRC and PM from Caris Life Sciences. Testing included next-generation sequencing of 592 genes, microsatellite instability (MSI) and tumor mutational burden (TMB). Mutations...

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Identifiers

PMID: 32166754
DOI: 10.1002/jso.25899
PMCID: PMC7505122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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