Article
The transition from primary colorectal cancer to isolated peritoneal malignancy is associated with an increased tumour mutational burden.
Scientific reports - 3 Nov 2020
Hallam Sally, Stockton Joanne, Bryer Claire, Whalley Celina, Pestinger Valerie, Youssef Haney, Beggs Andrew D
Abstract excerpt
Colorectal Peritoneal metastases (CPM) develop in 15% of colorectal cancers. Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS & HIPEC) is the current standard of care in selected patients with limited resectable CPM. Despite selection using known prognostic factors survival is varied and morbidity and mortality are relatively high. There is a need to improve patient selection and a paucity of...
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