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Human-engineered heart tissues recapitulate tissue-scale mechanisms underlying ventricular tachycardia

2026-02-14

Abstract excerpt

<h4>ABSTRACT</h4> Human iPSC-derived engineered heart tissues (EHTs) and cardiac organoids are increasingly used to model cardiac physiology and drug responses, yet it remains unclear whether they can reproduce tissue-scale mechanisms underlying ventricular arrhythmias. Advanced electrophysiological characterization of EHTs has been limited by the lack of a recording framework compatible with small, perfused prep...

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Literature Corpus work
da7e5f02-3529-528d-b500-2977f759499e
DOI
10.64898/2026.02.11.705466
Open publication

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Human-engineered heart tissues recapitulate tissue-scale mechanisms underlying ventricular tachycardiaDOI 10.64898/2026.02.11.705466
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