Article

Thymopoiesis, Alterations in Dendritic cells and Tregs and Reduced T-Cell Activation in Successful Extracorporeal Photopheresis Treatment of GVHD

2021-02-12

Abstract excerpt

<title>Abstract</title> <p>Acute graft-versus-host disease (aGVHD) is a significant complication of allogeneic hematopoietic stem cell transplant (HSCT) and negatively affects T-cell reconstitution. Extracorporeal photopheresis (ECP) reduces aGVHD, but the mechanisms remain incompletely understood. Our objective was to examine the impact of ECP on thymopoiesis in pediatric aGVHD and the mechanisms at a cellular a...

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Literature Corpus work: fee18d02-4114-5e6c-8a84-68dc3e3eed95
DOI: 10.21203/rs.3.rs-177137/v1

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