Article
CD4+CD25+ lymphocyte subsets in chronic graft versus host disease patients undergoing extracorporeal photochemotherapy.
International journal of immunopathology and pharmacology - 1 Jan 2000
Rubegni P, Sbano P, Cevenini G, Perari M G, Marotta G, Risulo M, Carcagnì M R, D' Ascenzo G, De Aloe G, Fimiani M
Abstract excerpt
Extracorporeal photochemotherapy (ECP) has been used successfully for the treatment of chronic Graft versus Host Disease (cGvHD). However, the mechanism by which ECP exerts its protective effects remains elusive. Some recent observations have suggested a possible role of certain subsets of T lymphocytes with immunosuppressive properties (T-regulatory cells) that coexpress CD4 and high levels of the interleukin-2...
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