Article

Nod2 protects remote small intestinal sites in case of colonic inflammation

2019-01-03

Abstract excerpt

<h4>ABSTRACT</h4> NOD2 mutations are key risk factors for Crohn’s disease (CD). NOD2 contributes to intestinal homeostasis by regulating innate and adaptive immunity together with intestinal epithelial function. However, the roles of NOD2 during gut inflammation is not known. We initially observed that NOD2 expression was increased in epithelial cells remote from inflamed areas in CD patients. To explore this fi...

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Literature Corpus work: fed94e36-edbc-5637-92e2-de139bbd5c8a
DOI: 10.1101/510933

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