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Article

Nod2: a key regulator linking microbiota to intestinal mucosal immunity.

Journal of molecular medicine (Berlin, Germany) - 1 Jan 2012

Biswas Amlan, Petnicki-Ocwieja Tanja, Kobayashi Koichi S

Abstract excerpt

The human intestine harbors a large number of bacteria that are constantly interacting with the intestinal immune system, eliciting non-pathological basal level immune responses. Increasing evidence points to dysbiosis of microbiota in the intestine as an underlying factor in inflammatory bowel disease susceptibility. Loss-of-function mutations in NOD2 are among the stronger genetic factors linked to ileal...

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Source

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Identifiers

PMID: 21861185
DOI: 10.1007/s00109-011-0802-y
PMCID: PMC3263373

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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