Article
Human genetics of HIV infection.
Current opinion in virology - 1 Sept 2026
Awada Abraham, Thorball Christian W, Timonina Valeriia, Carrington Mary, McLaren Paul J, Fellay Jacques
Abstract excerpt
Human Immunodeficiency Virus Type 1 (HIV-1) continues to pose a significant global public health challenge. Marked inter-individual variability in susceptibility to infection, viral load, and disease progression has long highlighted an important role for host genetic factors. To date, only a small number of germline loci show consistent, reproducible effects on HIV-1 control, most notably CCR5 and HLA class I...
Topics
- Humans
- HIV Infections
- HIV-1
- Genetic Predisposition to Disease
- Genetic Variation
- Host-Pathogen Interactions
- Receptors, CCR5