Article
Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations.
Cytokine - 1 Nov 2013
Lawhorn Collene, Yuferov Vadim, Randesi Matthew, Ho Ann, Morgello Susan, Kreek Mary Jeanne, Levran Orna
Abstract excerpt
BACKGROUND: Chemokine receptors CCR2 and CCR5 play a key role in immune and inflammatory responses and have been associated with several diseases, including AIDS. In order to comprehend health disparities it is important to understand the nature of genetic variation in specific genes of interest in different populations. Current studies of the CCR2 and CCR5 receptor genes are primarily focused on the CCR5-Δ32,...
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