Article

MiR-503-5p mediates cell cycle arrest and fibrosis of peritoneal mesothelial cells with a high peritoneal solute transport status

2025-05-29

Abstract excerpt

<title>Abstract</title> <p>Background Long-term peritoneal dialysis (PD) induces persistent inflammation and fibrosis of the peritoneal membrane (PM), altering the peritoneal solute transport rate (PSTR). We previously found elevated miR-503-5p levels in exosomes from PD effluent (PDE) in patients with high PSTR. As PSTR is strongly influenced by intraperitoneal inflammation, this study aimed to explore the rela...

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Literature Corpus work: fe535ea3-1507-54de-b2ee-191725196050
DOI: 10.21203/rs.3.rs-6537719/v1

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