Article
Epithelial-to-mesenchymal transition of mesothelial cells is an early event during peritoneal dialysis and is associated with high peritoneal transport.
Kidney international. Supplement - 1 Apr 2008
Del Peso G, Jiménez-Heffernan J A, Bajo M A, Aroeira L S, Aguilera A, Fernández-Perpén A, Cirugeda A, Castro M J, de Gracia R, Sánchez-Villanueva R, Sánchez-Tomero J A, López-Cabrera M, Selgas R
Abstract excerpt
Ultrafiltration (UF) failure is a consequence of long-term peritoneal dialysis (PD). Fibrosis, angiogenesis, and vasculopathy are causes of this functional disorder after 3-8 years on PD. Epithelial-to-mesenchymal transition (EMT) of mesothelial cell (MC) is a key process leading to peritoneal fibrosis with functional deterioration. Our purpose was to study the peritoneal anatomical changes during the first...
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