Article

Autophagy caused by oxidative stress promotes TGF-β1-induced epithelial-to-mesenchymal transition in human peritoneal mesothelial cells

2023-12-27

Abstract excerpt

<title>Abstract</title> <p>Epithelial-to-mesenchymal transition (EMT) is an important cause of peritoneal fibrosis. However, pathophysiological mechanism of EMT, specifically its relationship with autophagy, is still unknown. This study aimed to evaluate the role of autophagy in TGF-β1-induced EMT in human peritoneal mesothelial cells (HPMCs). Primary cultured HPMCs were treated with TGF-β1 (2 and 5 ng/mL) and ch...

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Literature Corpus work: d4f44933-7854-5846-a24a-f5ea66ca5abe
DOI: 10.21203/rs.3.rs-3659913/v1

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