Article

Targeting STING in experimental peritoneal damage: a novel approach in peritoneal dialysis therapy

2024-11-21

Abstract excerpt

Peritoneal dialysis (PD) is a widely used kidney replacement therapy for end-stage kidney disease (ESKD) patients. However, long-term exposure to PD fluids (PDF) can lead to peritoneal membrane (PM) damage, causing ultrafiltration failure and thus PD discontinuation. Investigating the molecular mechanisms underlying this damage is crucial for identifying new therapeutic targets to mitigate peritoneal deterioration...

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Literature Corpus work: 9f7d3ca5-167c-51e8-baa8-1774dd97c4b5
DOI: 10.1101/2024.11.19.621845

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