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NDUFV1 activation mediates high glucose-induced apoptosis in peritoneal mesothelial cells

2026-08-03

Abstract excerpt

Peritoneal mesothelial cells (PMCs) are critical components of the peritoneum, and prolonged exposure to high glucose in peritoneal dialysis fluid can lead to structural and functional impairment of the peritoneal membrane. However, whether such cellular damage is caused by glucose itself or by the hyperosmotic environment remains controversial. To elucidate the mechanisms underlying high glucose-induced PMCs apop...

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Literature Corpus work
f276f688-322d-5899-9047-62a3f5058ef7
DOI
10.1186/s13059-026-04227-3
Open publication

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NDUFV1 activation mediates high glucose-induced apoptosis in peritoneal mesothelial cellsDOI 10.1186/s13059-026-04227-3
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