Article

The conserved herpesviral kinase ORF36 activates B2 retrotransposons during murine gammaherpesvirus infection

2020-01-06

Abstract excerpt

<h4>ABSTRACT</h4> Short interspersed nuclear elements (SINEs) are RNA polymerase III (RNAPIII) transcribed, retrotransposable noncoding RNA (ncRNA) elements ubiquitously spread throughout mammalian genomes. While normally silenced in healthy somatic tissue, SINEs can be induced during infection with DNA viruses, including the model murine gammaherpesvirus MHV68. Here, we explored the mechanisms underlying MHV68 a...

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Literature Corpus work: fe4fbab9-6da9-5ecb-93e5-b4e04b4a7267
DOI: 10.1101/2020.01.06.895789

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