Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB Pathway

19 Nov 2015

Abstract excerpt

Short interspersed nuclear elements (SINEs) are highly abundant, RNA polymerase III-transcribed noncoding retrotransposons that are silenced in somatic cells but activated during certain stresses including viral infection. How these induced SINE RNAs impact the host-pathogen interaction is unknown. Here we reveal that during murine gammaherpesvirus 68 (MHV68) infection, rapidly induced SINE RNAs activate the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cytomegalovirus and herpesvirus research
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26584434
DOI: 10.1371/journal.ppat.1005260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infection-Induced Retrotransposon-Derived Noncoding RNAs Enhance Herpesviral Gene Expression via the NF-κB PathwayPMID 26584434Read ↗

Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signalingSemantic proximity Read ↗

The conserved herpesviral kinase ORF36 activates B2 retrotransposons during murine gammaherpesvirus infectionSemantic proximity Read ↗

Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKKβ to Initiate Lytic ReplicationSemantic proximity Read ↗

Endogenous Retroviruses as Modulators of Innate ImmunitySemantic proximity Read ↗

RNA helicases, DDX5 and DDX17, facilitate lytic reactivation of gammaherpesvirusesSemantic proximity Read ↗

A Gammaherpesvirus Cooperates with Interferon-alpha/beta-Induced IRF2 to Halt Viral Replication, Control Reactivation, and Minimize Host LethalitySemantic proximity Read ↗

Transactivation of human endogenous retroviruses by tumor viruses and their functions in virus-associated malignanciesSemantic proximity Read ↗

γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesisSemantic proximity Read ↗

Non-Coding RNAs and Immune Evasion in Human Gamma-HerpesvirusesSemantic proximity Read ↗

Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinerySemantic proximity Read ↗

Sendai Virus Infection Induces Expression of Novel RNAs in Human CellsSemantic proximity Read ↗

Herpesvirus Epigenetic Reprogramming and OncogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.