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Article

Sp140L Is a Novel Herpesvirus Restriction Factor

2024-12-14

Abstract excerpt

Herpesviruses, including Epstein-Barr Virus (EBV) – a human oncogenic viruses and essential trigger of multiple sclerosis, must bypass host DNA sensing mechanisms to establish lifelong, latent infection. Therefore, herpesviruses encode viral proteins to disrupt key host factors involved in DNA sensing and viral restriction. The first viral latency protein expressed, EBNA-LP, is essential for transformation of naïv...

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Literature Corpus work
36a96004-634a-5aaa-82b0-183a3ada5a53
DOI
10.1101/2024.12.13.628399
Open publication

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Sp140L Is a Novel Herpesvirus Restriction FactorDOI 10.1101/2024.12.13.628399
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