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Article

Virus-encoded microRNAs facilitate gammaherpesvirus latency and pathogenesis in vivo.

mBio - 27 May 2014

Feldman Emily R, Kara Mehmet, Coleman Carrie B, Grau Katrina R, Oko Lauren M, Krueger Brian J, Renne Rolf, van Dyk Linda F, Tibbetts Scott A

Abstract excerpt

UNLABELLED: Gammaherpesviruses, including Epstein-Barr virus (EBV), Kaposi sarcoma-associated herpesvirus (KSHV, or HHV-8), and murine gammaherpesvirus 68 (MHV68, γHV68, or MuHV-4), are B cell-tropic pathogens that each encode at least 12 microRNAs (miRNAs). It is predicted that these regulatory RNAs facilitate infection by suppressing host target genes involved in a wide range of key cellular pathways. However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24865551
DOI: 10.1128/mBio.00981-14
PMCID: PMC4045068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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