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Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signaling

2022-07-10

Abstract excerpt

RNA polymerase III (RNAPIII) transcribes a variety of noncoding RNAs, including transfer RNA (tRNA) and the B2 family of short interspersed nuclear elements (SINEs). B2 SINEs are noncoding retrotransposons that possess tRNA-like promoters and are normally silenced in healthy somatic tissue. Infection with the murine gammaherpesvirus MHV68 induces transcription of both SINEs and tRNAs, in part through the activity...

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Literature Corpus work
5fb8b92b-e1b3-58fc-ad61-9d3e2d67f78a
DOI
10.1101/2022.07.09.499448
Open publication

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Murine gammaherpesvirus 68 ORF45 stimulates B2 retrotransposon and pre-tRNA activation in a manner dependent on mitogen-activated protein kinase (MAPK) signalingDOI 10.1101/2022.07.09.499448
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