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Article

RIG‐I is a key antiviral interferon‐stimulated gene against hepatitis E virus regardless of interferon production

13 Feb 2017

Abstract excerpt

Interferons (IFNs) are broad antiviral cytokines that exert their function by inducing the transcription of hundreds of IFN-stimulated genes (ISGs). However, little is known about the antiviral potential of these cellular effectors on hepatitis E virus (HEV) infection, the leading cause of acute hepatitis globally. In this study, we profiled the antiviral potential of a panel of important human ISGs on HEV...

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PMID: 28195391
DOI: 10.1002/hep.29105

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