Article

Phenotype-specific associations of mosaic chromosomal alterations in systemic sclerosis

2026-03-03

Abstract excerpt

<h4>Objectives</h4> Mosaic chromosomal alterations (mCAs) increase with age and are associated with many diseases, including autoimmune diseases. The associations between mCAs and systemic sclerosis (SSc) and its clinical subtypes have not been explored. <h4>Methods</h4> We recruited study subjects from two independent datasets (Set 1: 635 SSc, 4,401 controls; Set 2: 347 SSc, 2,170 controls) and detected mCAs (L...

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Literature Corpus work: fe1e3a6a-5bb3-51db-bc91-326bfa564a03
DOI: 10.64898/2026.03.02.26347384

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