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Epigenetics and systemic sclerosis: An answer to disease onset and evolution?

20 Jul 2020

Abstract excerpt

There is growing evidence that implicates epigenetic modification in the pathogenesis of systemic sclerosis (SSc). The complexity of epigenetic regulation and its dynamic nature complicate the investigation of its role in the disease. We will review the current literature for factors that link epigenetics to SSc by discussing DNA methylation, histone acetylation and methylation, and non-coding RNAs (ncRNAs),...

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PMID: 32697935
DOI: 10.5152/eurjrheum.2020.19112

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