Article

Loss of cell cycle control renders cells nonresponsive to local extrinsic differentiation cues

2019-07-30

Abstract excerpt

<h4>Objective and approaches</h4> Aberrantly proliferating cells are linked to a number of diseases including cancers and developmental defects.To determine the extent to which local extrinsic signals contribute to or ameliorate mutant cell behaviors, we examined survival and differentiation of mutant cells in wild-type retinal environments by generating chimeric zebrafish embryos comprised of unlabeled host cell...

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Literature Corpus work: fdc7ff1a-bb1c-56e8-84c3-8dc6344316cb
DOI: 10.1101/720276

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