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Article

Cyclin E and CDK2 repress the terminal differentiation of quiescent cells after asymmetric division in C. elegans.

PloS one - 2 May 2007

Fujita Masaki, Takeshita Hisako, Sawa Hitoshi

Abstract excerpt

Coordination between cell proliferation and differentiation is important in normal development and oncogenesis. These processes usually have an antagonistic relationship, in that differentiation is blocked in proliferative cells, and terminally differentiated cells do not divide. In some instances, cyclins, cyclin-dependent kinases (CDKs) and their inhibitors (CKIs) play important roles in this antagonistic...

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Identifiers

PMID: 17476329
DOI: 10.1371/journal.pone.0000407
PMCID: PMC1852333

Genes

CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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