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Article

Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF.

Molecular biology of the cell - 1 Aug 2008

Pomerening Joseph R, Ubersax Jeffrey A, Ferrell James E

Abstract excerpt

In Xenopus embryos, the cell cycle is driven by an autonomous biochemical oscillator that controls the periodic activation and inactivation of cyclin B1-CDK1. The oscillator circuit includes a system of three interlinked positive and double-negative feedback loops (CDK1 -> Cdc25 -> CDK1; CDK1 -/ Wee1 -/ CDK1; and CDK1 -/ Myt1 -/ CDK1) that collectively function as a bistable trigger. Previous work established...

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CDC2 Protein Kinase
Cell Cycle
Cyclin B
Cyclin B1
G1 Phase
Mitosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein-Tyrosine Kinases

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Identifiers

PMID: 18480403
DOI: 10.1091/mbc.e08-02-0172
PMCID: PMC2488275

Genes

CDK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF.PMID 18480403Read ↗

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