Article

Derivation of oligodendrocyte precursor cells from human bone marrow stromal cells and use for re-myelination in the congenitally dysmyelinated brain

2019-06-17

Abstract excerpt

<h4>ABSTRACT/ SUMMARY</h4> Oligodendrocytes (OLs) are the only myelinating glia in the central nervous system (CNS). In congenital myelin disorders, OL dysfunction or death results in loss of myelin. This causes progressive and irreversible impairment to motor and cognitive functions, and is amongst the most disabling neurological disorder. Neonatal engraftment by glial progenitor cells (GPCs) allows the robust m...

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Literature Corpus work: fdb914af-ade0-5ae8-8624-fb4c9cfb3bb1
DOI: 10.1101/658997

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