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Stem Cell-Derived Oligodendroglial Cells for Therapy in Neurological Diseases.

Current stem cell research & therapy - 1 Jan 2016

García-León Juan A, Verfaillie Catherine M

Abstract excerpt

There are an important number of neurological diseases where not neurons but glia are the responsible cells for the degeneration of the nervous system. In the last years, determinant roles for oligodendrocytes (OLs) have been demonstrated not only in myelin generation and maintenance but also for metabolic support of neurons. Oligodendroglial defects lead to brain degeneration in several diseases, supporting the...

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Cell Separation
Nervous System Diseases
Oligodendroglia
Phenotype
Stem Cell Transplantation

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PMID: 26329482
DOI: 10.2174/1574888x10666150902095312

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