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Article

Adult brain retains the potential to generate oligodendroglial progenitors with extensive myelination capacity.

Proceedings of the National Academy of Sciences of the United States of America - 30 Mar 1999

Zhang S C, Ge B, Duncan I D

Abstract excerpt

Remyelination of focal areas of the central nervous system (CNS) in animals can be achieved by transplantation of glial cells, yet the source of these cells in humans to similarly treat myelin disorders is limited at present to fetal tissue. Multipotent precursor cells are present in the CNS of adult as well as embryonic and neonatal animals and can differentiate into lineage-restricted progenitors such as...

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Identifiers

PMID: 10097168
DOI: 10.1073/pnas.96.7.4089
PMCID: PMC22425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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