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Human Embryonic Stem Cell-Derived Oligodendrocytes: Protocols and Perspectives

28 Apr 2013

Abstract excerpt

Oligodendrocytes play a fundamental supportive role in the mammalian central nervous system (CNS) as the myelinating-glial cells. Disruption of fast axonal transport mechanisms can occur as a consequence of mature oligodendrocyte loss following spinal cord injury, stroke, or due to neuroinflammatory conditions, such as multiple sclerosis. As a result of the limited remyelination ability in the CNS after injury or...

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PMID: 23621561
DOI: 10.1089/scd.2012.0520

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