Article

Rapid and efficient generation of human oligodendrocytes myelinating adult human cortical neurons

2025-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Intracerebral transplantation of stem cell-derived oligodendrocytes (OLs) holds promise as a new strategy for repairing demyelinated brain tissue. However, two challenges hinder clinical translation: the slow and inefficient generation of human OLs for transplantation using the protocols described to date, and the limited insight into their remyelination potential, which has only been evaluated...

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Literature Corpus work: 6f8a3092-7088-5a52-852c-7bce4321d2fb
DOI: 10.1101/2025.02.28.640804

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