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Molecular Determinants of Severe Acute Respiratory Syndrome Coronavirus Pathogenesis and Virulence in Young and Aged Mouse Models of Human Disease

2020-04-10

Abstract excerpt

SARS coronavirus (SARS-CoV) causes severe acute respiratory tract disease characterized by diffuse alveolar damage and hyaline membrane formation. This pathology often progresses to acute respiratory distress (such as acute respiratory distress syndrome [ARDS]) and atypical pneumonia in humans, with characteristic age-related mortality rates approaching 50% or more in immunosenescent populations. The molecular bas...

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SARS-CoV-2 and COVID-19 Research

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Literature Corpus work: fd97dae5-0192-57b6-a0a1-602df9fce236
DOI: 10.17615/r492-2528

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