Article

Engineering a mouse-adapted SADS-CoV and establishing a neonatal mouse model to study its infection

2025-06-02

Abstract excerpt

Swine acute diarrhea syndrome coronavirus (SADS-CoV) is an emerging bat-origin alphacoronavirus causing severe disease in neonatal piglets, with significant economic losses to the swine industry as a consequence. The virus exhibits a broad species tropism, infecting cells derived from pigs, humans and mice, highlighting its potential for cross-species transmission. Due to drawbacks associated with the use of young...

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Literature Corpus work: ad299091-28f2-57ab-ae19-16c56d3b6b12
DOI: 10.1101/2025.06.02.657353

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